Lei Feng

Biomolecular condensation of ERC1 recruits ATG8 and NBR1 to drive autophagosome formation for plant heat tolerance

This study identifies ERC1 as a protein that forms biomolecular condensates to recruit ATG8 and NBR1, promoting autophagosome formation and enhancing heat tolerance in Arabidopsis.

Gut metagenomes of Asian octogenarians reveal metabolic potential expansion and distinct microbial species associated with aging phenotypes

The paper analyzes gut metagenomes of Asian octogenarians to identify age-related microbial shifts and their associations with aging phenotypes.

sRNAanno --- a database repository of uniformly-annotated small RNAs in plants

sRNAanno provides a comprehensive database of uniformly-annotated small RNAs in 138 plant species, including miRNAs, phasiRNAs, and hc-siRNAs, along with a visualization tool for NGS sRNA data.

Key Nucleation Stages and Associated Molecular Determinants and Processes in pH-Induced Formation of Amyloid Beta Oligomers as Revealed by High-Speed AFM

This study uses high-speed AFM to visualize pH-induced AB42 peptide nucleation and identifies key molecular stages in oligomer formation.

Analysis of genomic DNA methylation and gene transcription modulation induced by DNMT3A deficiency in HEK293 cells

This study investigates the effects of DNMT3A deficiency on DNA methylation and gene expression in HEK293 cells, revealing reduced methylation and altered gene regulation.

A Reference Feature based method for Quantification and Identification of LC-MS based untargeted metabolomics

This paper introduces RFQI, a reference-feature based method for quantification and identification in LC-MS untargeted metabolomics, improving batch consistency and metabolite detection efficiency.

Protein Deacetylase CobB Interplays with c-di-GMP

The paper identifies a novel negative feedback loop where c-di-GMP inhibits CobB activity, modulating acetyl-CoA biogenesis and YdeH stability and cyclase activity.