Systems BiologyCell ReportsPeer-reviewed
Cell-to-cell variability in JAK2/STAT5 pathway components and cytoplasmic volumes define survival threshold in erythroid progenitor cells
Lorenz Adlung, Paul L. Stapor, Christian Tönsing…·Marcel Schilling
The paper models single-cell variability in JAK2/STAT5 signaling and cytoplasmic volume to explain how erythroid progenitor cells transition from binary survival/apoptosis decisions to graded population responses upon Epo stimulation.
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