ImmunologybioRxivPreprint
A novel CAR T cell blend targeting PDPN and GD2 to overcome glioblastoma heterogeneity
Vera Nickl, Julian Hübner, Marah Alsalkini…·Thomas Nerreter
This paper develops a PDPN- and GD2-targeting CAR T cell blend to overcome glioblastoma heterogeneity, showing improved anti-tumor activity in organoids and increased survival in mice.
DOI 10.1101/2025.02.03.636223