Distinct maternofetal immune signatures delineate preterm birth onset following urinary tract infection
Samantha Ottinger, Addison B. Larson, Vicki Mercado-Evans, Holly Branthoover, Jacob J. Zulk, Camille Serchejian, Libbie Ogilvie, Marlyd E. Mejia, Zainab A. Hameed, Ryan Walde, Rachel C. Fleck, Christopher Scott Ward, Allyson E. Shea, Kathryn A. Patras
This study identifies immune signatures in mice and human urine that predict preterm birth risk following UTI, highlighting cytokines like IL-10 and IL-15 as potential therapeutic targets.
Science Translational Medicine · Aug 26, 2026Peer-reviewedImmunology