GeneticsbioRxivPreprint
Coupling multiplex pre-amplification and droplet digital PCR for longitudinal monitoring of ESR1 and PIK3CA mutations from plasma cell-free DNA
Huilan Yao, Grant Wu, Subhasree Das…·Pavan Kumar
This paper develops a method combining multiplex pre-amplification and ddPCR to detect ESR1 and PIK3CA mutations in plasma cfDNA from MBC patients, achieving high sensitivity and reproducibility.
DOI 10.1101/598847