Author

Lijuan Chang

Henan Agricultural University

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Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Organism:E. coli· 1 Approach:experimental assay· 1

Frequent Co-Authors

Chenglong LiiD· 1 shared Dexi Li· 1 shared Štefan SchwarziD· 1 shared Xiang‐Dang DuiD· 1 shared Xiaoming WangiD· 1 shared Xinyu GuoiD· 1 shared Yage SuniD· 1 shared Yanling WangiD· 1 shared

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2025-2025 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperPharmacology & Toxicology

Chenglong LiORCID

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1 paper

Recent·Most cited

Pharmacology & ToxicologybioRxivPreprintMar 31, 2025

Restoration of Susceptibility of blaNDM-bearing Escherichia. coli to Carbapenem Antibiotics by Exogenous N-acetylcysteine

Dexi Li, Yuzhe Zhao, Xinyu Guo…·Xiang‐Dang Du

This study shows that N-acetylcysteine restores carbapenem susceptibility in NDM-producing E. coli through three mechanisms: inhibiting biofilm formation, downregulating blaNDM-5, and enhancing meropenem intracellular accumulation.

DOI 10.1101/2025.03.31.646374

E. coliexperimental assay

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