Author

Lin Zeng

Shanghai Jiao Tong University

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Biology Disciplines

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Evolutionary Biology· 1 Genetics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:C. elegans· 1 Research Focus:database / resource· 1 Organism:human· 1 Organism:mouse· 1 Research Focus:phylogenetics / evolution· 1 Assay:proteomics· 1 Organism:rat· 1

Frequent Co-Authors

En-Zhi SheniD· 2 shared Ali Esmailizadeh· 1 shared Ambroise DaleckyiD· 1 shared Chen Ming· 1 shared Chun‐Qing SongiD· 1 shared David M. Irwin· 1 shared David R. SherwoodiD· 1 shared Dengfeng LiiD· 1 shared

Activity by Year

2016-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersGenetics

En-Zhi ShenORCID

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Author profile →

3 papers

Recent·Most cited

WormTagDB: A Systematic Survey of Endogenously Tagged Proteins in C. elegans and Roadmap Towards the Tagged Proteome

Jake Leyhr, Qiuyi Chi, Lin Zeng, En-Zhi Shen, Wei Zou, David R. Sherwood

The paper catalogs endogenously tagged proteins in C. elegans, identifies gaps in coverage, and provides a database with tools for designing knock-in experiments.

bioRxiv · Dec 5, 2025 · PreprintGenetics

Mammalian PIWI-piRNA-target complexes reveal features for broad and efficient target-silencing

Zhiqing Li, Zhenzhen Li, Yuqi Zhang, Lunni Zhou, Qikui Xu, Lili Li, Lin Zeng, Junchao Xue, Huilin Niu, Jing Zhong, Qilu Yu, Dengfeng Li, Miao Gui, Yongping Huang, Shikui Tu, , En-Zhi Shen

This study reveals structural and functional features of mammalian PIWI-piRNA-target complexes that enable efficient and broad target silencing.

Nature Structural & Molecular Biology · Apr 24, 2024Peer-reviewedMolecular Biology

Evolutionary history of the brown rat: out of southern East Asia and selection

Lin Zeng, Chen Ming, Yan Li, Ling-Yan Su, Yan-Hua Su, Newton O. Otecko, Ambroise Dalecky, Stephen Donnellan, Ken Aplin, Xiao-Hui Liu, Ying Song, Zhi-Bin Zhang, Ali Esmailizadeh, Saeed S. Sohrabi, Hojjat Asadollahpour Nanaei, , Ya-Ping Zhang

This study sequenced whole genomes of 118 brown rats to trace their origin, migration routes, and domestication, finding they originated in southern East Asia and showing evidence of selection in immune and domestication-related genes.

bioRxiv · Dec 26, 2016 · PreprintEvolutionary Biology