Author

Linshu Li

Southern University of Science and Technology

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:bacteria (other)· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Hua Qi· 2 shared Juntao ZhangiD· 2 shared Xin-Yang WeiiD· 2 shared Xin-Yi Song· 2 shared Yushan XiaiD· 2 shared Ainan GengiD· 1 shared Hashim M. Al‐HashimiiD· 1 shared Jia NingiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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2 shared papersMicrobiology

Hua Qi

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Dual phage sensing activates an RNA-targeting reverse transcriptase for anti-phage defense

Xin-Yang Wei, Hua Qi, Xin-Yi Song, Linshu Li, Yushan Xia, Juntao Zhang, Jia Ning

This study identifies DRT4 as a dual-sensor immune system that uses phage-derived signals to activate an RNA-targeting reverse transcriptase for anti-phage defense.

bioRxiv · Oct 27, 2026 · PreprintMicrobiology

Antiviral reverse transcriptase-primase synthesizes protein-templated DNA

Xin-Yi Song, Yushan Xia, Juntao Zhang, Xin-Yang Wei, Hua Qi, Linshu Li, Ning Jia

This study shows DRT7, a reverse transcriptase-primase, generates protein-templated DNA to provide broad-spectrum antiviral immunity through abortive infection.

bioRxiv · Apr 19, 2026 · PreprintMicrobiology

An A-T Hoogsteen base pair in a naked DNA hairpin motif: A Protein-Recognized Conformation

Serafima Guseva, Or Szekely, Ainan Geng, Kai Smith, Supriya Pratihar, Yeongjoon Lee, Linshu Li, Sophie Marianne Korn, Stephanie Gu, Hashim M. Al‐Hashimi

The paper shows that an A-T Hoogsteen base pair forms in naked DNA hairpins without protein binding, and identifies a DNA-specific motif stabilized by this pairing.

Angewandte Chemie International Edition · Apr 11, 2025Peer-reviewedBiochemistry