Genetic & Genomic MedicinemedRxivPreprint
Multi-PGS enhances polygenic prediction: weighting 937 polygenic scores
Clara Albiñana, Zhihong Zhu, Andrew Joseph Schork…·Bjarni Jóhann Vilhjálmsson
This paper introduces a framework to enhance polygenic prediction by combining multiple polygenic scores, showing significant accuracy improvements for psychiatric disorders and other traits.
10 citations