Lorna Ewart

This paper describes a bone marrow-on-a-chip model that supports long-term cultivation and differentiation of human hematopoietic stem and progenitor cells, demonstrating its utility for drug testing and transplantation studies.

The paper describes a Bone Marrow-on-a-Chip model that mimics bone marrow function and disease states, including drug and radiation responses and Shwachman-Diamond Syndrome abnormalities.