Author

M. A. Hassert

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 4 Immunology· 1 Plant Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Research Focus:host-pathogen & immune response· 4 Research Focus:drug response / drug discovery· 2 Organism:mouse· 2 Organism:Arabidopsis· 1 Research Focus:cell type annotation· 1 Organism:non-human primate· 1 Organism:rat· 1

Frequent Co-Authors

A. K. Pinto· 5 shared J. D. Brien· 4 shared A. de Silva· 2 shared C. A. Sariol· 2 shared C. Serrano-Collazo· 2 shared E. X. Perez-Guzman· 2 shared I. V. Rodriguez· 2 shared L. J. White· 2 shared

Activity by Year

2018-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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5 shared papersMicrobiology

A. K. Pinto

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Metal Coordinating Inhibitors of Rift Valley Fever virus Replication

E. Geerling, V. Murphy, E. T. Stone, A. G. Casals, M. A. Hassert, A. T. O'Dea, F. Cao, M. J. Donlin, B. E.-D. M. Elgendy, M. Elagawany, V. Pardali, E. Giannakopoulou, G. Zoidis, D. V. Schiavone, A. J. Berkowitz, , J. D. D. Brien

This study identifies 31 novel RVFV replication inhibitors with selective indexes and effective concentrations, primarily -Hydroxytropolones and N-Hydroxypyridinediones, validated in human cells and tested against related Bunyaviruses.

bioRxiv · Mar 10, 2022Microbiology

A mRNA-LNP vaccine against Dengue Virus elicits robust, serotype-specific immunity

C. J. Wollner, M. C. Richner, M. A. Hassert, A. K. Pinto, J. D. Brien, J. M. Richner

This paper develops an mRNA-LNP vaccine against Dengue Virus serotype 1 that elicits strong, serotype-specific immunity with reduced antibody-dependent enhancement.

bioRxiv · Jan 5, 2021 · PreprintMicrobiology

Heterologous flavivirus exposure provides varying degrees of cross-protection from Zika virus in a mouse model of infection

M. A. Hassert, S. Scroggins, A. K. Coleman, E. Shacham, J. D. Brien, A. K. Pinto

This study shows that prior exposure to different flaviviruses provides varying levels of protection against Zika virus in mice, with primary Zika infection being most protective.

bioRxiv · Dec 23, 2020 · PreprintMicrobiology

Significant control of Zika infection in macaques depends on the elapsing time after dengue exposure

C. Serrano-Collazo, E. X. Perez-Guzman, P. Pantoja, M. A. Hassert, I. V. Rodriguez, L. D. Giavedoni, V. Hodara, L. Parodi, L. A. Cruz, T. Arana, M. I. Martinez, L. J. White, J. D. Brien, A. de Silva, A. K. Pinto, C. A. Sariol

The paper shows that a longer interval between dengue and Zika infections improves Zika control in macaques, linked to pre-existing CD4+ T cell responses rather than antibodies.

bioRxiv · Sep 6, 2019 · PreprintImmunology

Time elapsed between Zika and dengue virus infections affects antibody and T cell responses

E. X. Perez-Guzman, P. Pantoja, C. Serrano-Collazo, M. A. Hassert, A. Ortiz-Rosa, I. V. Rodriguez, L. Giavedoni, V. Hodara, L. Parodi, L. Cruz, T. Arana, L. J. White, M. I. Martinez, D. Weiskopf, J. D. Brien, , C. A. Sariol

This study examines how the time between Zika and dengue virus infections affects immune responses, finding that prior Zika exposure enhances antibody and T cell responses to dengue without increasing viremia.

bioRxiv · Aug 26, 2019Microbiology

Functional dissection of the ARGONAUTE7 promoter

J. S. Hoyer, J. L. Pruneda-Paz, G. Breton, M. A. Hassert, E. E. Holcomb, H. Fowler, K. M. Bauer, J. Mreen, S. A. Kay, J. C. Carrington

The paper identifies transcription factors binding to the ARGONAUTE7 promoter in Arabidopsis thaliana and shows that SPL and TCP families are involved, though not essential for AGO7 function or expression pattern.

bioRxiv · Nov 24, 2018Plant Biology