Structure of RADX and mechanism for regulation of RAD51 nucleofilaments
S. Balakrishnan, M. Adolph, M.-s. Tsai, K. Gallagher, D. Cortez, W. J. Chazin
This paper investigates the structure and mechanism of RADX, a negative regulator of RAD51 nucleofilaments, showing it caps and restricts RAD51 filament growth to regulate replication fork reversal.
bioRxiv · Sep 19, 2023 · PreprintBiophysics