Author

S. Balakrishnan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2 Cancer Biology· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1

Frequent Co-Authors

A. Abu Rmaileh· 1 shared A. Barua· 1 shared A. Khatib· 1 shared A. M. Orriols· 1 shared A. Vassilopoulos· 1 shared C. Yau· 1 shared C. Yeh· 1 shared D. Cortez· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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1 shared paperCancer Biology

A. Abu Rmaileh

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

S100A8/A9 predicts triple-negative breast cancer response to PIM kinase and PD-1/PD-L1 inhibition

L. R. Begg, A. M. Orriols, M. Zannikou, C. Yeh, P. Vadlamani, D. Kanojia, R. Bolin, S. F. Dunne, S. Balakrishnan, R. Camarda, D. Roth, N. A. Zielinski-Mozny, C. Yau, A. Vassilopoulos, T.-H. Huang, , D. Horiuchi

bioRxiv · Sep 21, 2023 · PreprintCancer Biology

Structure of RADX and mechanism for regulation of RAD51 nucleofilaments

S. Balakrishnan, M. Adolph, M.-s. Tsai, K. Gallagher, D. Cortez, W. J. Chazin

This paper investigates the structure and mechanism of RADX, a negative regulator of RAD51 nucleofilaments, showing it caps and restricts RAD51 filament growth to regulate replication fork reversal.

bioRxiv · Sep 19, 2023 · PreprintBiophysics

Predicting the tension in actin cytoskeleton from the nucleus shape

S. Balakrishnan, S. R. Raju, A. Barua, G. K. Ananthasuresh

The paper develops a computational method to estimate actin cytoskeletal tension from nuclear shape using geometric parameters and validates it through experimental modulation.

bioRxiv · Aug 28, 2020 · PreprintBiophysics

Glutathione Peroxidase 8 (GPX8)-IL6 axis is essential in maintaining breast cancer mesenchymal stem-like state and aggressive phenotype

A. Khatib, S. Balakrishnan, M. Ben-Yosef, G. Oren, A. Abu Rmaileh, M. Schlesinger, J. H. Axelrod, M. Lichtenstein, Y. D. Shaul

This study identifies the GPX8-IL6 axis as a key driver of the mesenchymal stem-like state and aggressive phenotype in breast cancer.

bioRxiv · Oct 25, 2019 · PreprintCancer Biology