Author

M. Bacchetta

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cell Biology· 2

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

A. J. Gutierrez· 1 shared B. Wehrle-Haller· 1 shared C. J. Taylor· 1 shared C. S. Jetter· 1 shared J. A. Kropski· 1 shared J. E. Camarata· 1 shared J. J. Gokey· 1 shared J. M. S. Sucre· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperCell Biology

A. J. Gutierrez

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Akt Drives TGF-beta-induced Over-secretion of DKK1 and Impairment of Cystic Fibrosis Airway Epithelium Polarity

T. Idris, M. Bachmann, M. Bacchetta, B. Wehrle-Haller, M. Chanson, M. Badaoui

This study shows that Akt signaling drives TGF-beta-induced over-secretion of DKK1 and impairs apicobasal polarity in CF airway epithelium, with therapeutic targeting of these pathways restoring polarization.

bioRxiv · May 22, 2023 · PreprintCell Biology

Single-cell transcriptomic assessment of cellular phenotype stability in human precision-cut lung slices

N. I. Winters, C. J. Taylor, C. S. Jetter, J. E. Camarata, A. J. Gutierrez, L. T. Bui, J. J. Gokey, M. Bacchetta, N. E. Banovich, J. M. S. Sucre, J. A. Kropski

The paper compares single-cell transcriptomic profiles of human PCLS after five days of culture to freshly isolated lung tissue, finding changes in endothelial and alveolar epithelial cell programs but stable immune cell profiles.

bioRxiv · Aug 19, 2021 · PreprintCell Biology