M. Bachmann

Metatranscriptomic analysis reveals synergistic activities of comammox and anammox bacteria in full-scale attached growth nitrogen removal system.

The paper investigates how dissolved oxygen affects the synergistic nitrogen removal by comammox and anammox bacteria in wastewater treatment systems.

Akt Drives TGF-beta-induced Over-secretion of DKK1 and Impairment of Cystic Fibrosis Airway Epithelium Polarity

This study shows that Akt signaling drives TGF-beta-induced over-secretion of DKK1 and impairs apicobasal polarity in CF airway epithelium, with therapeutic targeting of these pathways restoring polarization.

New tools to study the interaction between integrins and latent TGFbeta1

The paper develops new tools to study how integrin Vβ6 interacts with latent TGFβ1, revealing unique mechanical rearrangements and binding differences with LAP1 and LAP3.

Co-occurrence and cooperation between comammox and anammox bacteria in a full-scale attached growth municipal wastewater treatment process.

The paper reports co-occurrence and cooperation between comammox and anammox bacteria in a full-scale wastewater treatment system, showing dissolved oxygen-dependent nitrogen loss.

AA-amyloidosis in cats (Felis catus) housed in shelters

The paper reports high prevalence of AA-amyloidosis in sheltered cats, linking shelter stay duration to disease severity and identifying SAA as the causative protein.

Voltage-Gated Potassium Channel Kv1.3 as a Therapeutic Target for Pancreatic Ductal Adenocarcinoma

This study shows Kv1.3 is highly expressed in human PDAC and novel Kv1.3 inhibitors combined with chemotherapy significantly reduce tumor growth in mouse models.

Phosphorylated paxillin and FAK constitute subregions within focal adhesions

The paper uses super-resolution microscopy to show that phosphorylated paxillin and FAK form spatially defined clusters within focal adhesions, which are mechanosensitive and dynamic.

Ligand binding promiscuity of αVβ3 integrin is enlarged in response to mechanical force

This study shows that mechanical force increases the ligand promiscuity of αVβ3 integrin by enabling binding to fibronectin through conformational changes.