Author

M. Beard

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Assay:protein structure· 1 Research Focus:protein structure prediction· 1 Assay:proteomics· 1

Frequent Co-Authors

D. Burgin· 1 shared F. A. Bard· 1 shared F. Hornby· 1 shared F. Tay· 1 shared G. Masuyer· 1 shared J. Maignel· 1 shared J. Philippe· 1 shared J. Skerlova· 1 shared

Activity by Year

2023-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperBiochemistry

D. Burgin

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2 papers

Recent·Most cited

Botulinum toxin intoxication requires retrograde transport and membrane translocation at the ER

Y. C. Jeremy, F. Tay, R. E. Bennion, O. Loss, J. Maignel, L. Pons, K. Foster, M. Beard, F. A. Bard

This study identifies genes and trafficking processes involved in botulinum toxin A intoxication, revealing a complex route involving retrograde transport and ER membrane translocation.

bioRxiv · Oct 17, 2023Cell Biology

Structure and activity of botulinum neurotoxin X

M. Martinez-Carranza, J. Skerlova, P.-G. Lee, J. Zhang, D. Burgin, M. Elliott, J. Philippe, S. Donald, F. Hornby, L. Henriksson, G. Masuyer, M. Beard, M. Dong, P. Stenmark

The paper presents the cryo-EM structure of BoNT/X-NTNH/X complex and shows its stability and low potency due to weak receptor-binding properties.

bioRxiv · Jan 11, 2023 · PreprintBiochemistry