Pharmacology & ToxicologybioRxiv
A small-molecule oral agonist of the human glucagon-like peptide-1 receptor
D. A. Griffith, D. J. Edmonds, J.-P. Fortin…·D. A. Tess
The paper describes an orally bioavailable small molecule agonist of the GLP-1R that lowers blood glucose in humans.
DOI 10.1021/acs.jmedchem.1c01856