Cytokine-Mediated Degradation of the Transcription Factor ERG Impacts the Pulmonary Vascular Response to Systemic Inflammatory Challenge
C. Schafer, S. Martin-Almedina, K. Kurylowicz, N. P. Dufton, L. Osuna-Almagro, M.-L. Wu, C. Johnson, A. Shah, D. O. Haskard, A. Buxton, E. Willis, K. Wheeler, S. Turner, M. Chlebicz, R. Scott, , C. T. Griffin
This study shows cytokine-induced degradation of ERG in lung endothelial cells leads to vascular hyperpermeability and inflammation during infection.
bioRxiv · Feb 8, 2023Cell Biology