Discovery of a Novel, Selective and Short-Acting Skeletal Myosin II Inhibitor
L. Radnai, M. Surman, M. Hafenbreidel, E. J. Young, R. F. Stremel, L. Lin, P. Pasetto, X. Jin, M. Geedy, J.-R. Partridge, A. Patel, M. Conlon, J. R. Sellers, M. D. Cameron, G. Rumbaugh, , C. A. Miller
This study discovers and characterizes skeletostatins, selective skeletal myosin II inhibitors with improved properties for research and drug development.
bioRxiv · Jul 28, 2020 · PreprintPharmacology & Toxicology