Keratinocytes coordinate inflammatory responses and regulate development of secondary lymphedema
H. Park, R. P. Kataru, J. Shin, G. D. Garcia Nores, E. M. Encarnacion, M. G. Klang, E. Riedel, M. Coriddi, J. H. Dayan, B. J. Mehrara
This study shows keratinocytes drive secondary lymphedema by producing Th2 cytokines and that targeting their activation can reduce inflammation and swelling in mice.
bioRxiv · Jan 20, 2023 · PreprintImmunology