M. D. Miller

The paper directly observes fast ligand binding in a biomedically relevant enzyme using MHz X-ray pulses at the European XFEL.

This study characterizes a phage ferredoxin from Prochlorococcus marinus, showing structural similarity to cyanobacterial ferredoxins and functional electron transfer to a host sulfite reductase.

This paper demonstrates a method to capture enzyme reactions in real-time using mix-and-inject serial crystallography, revealing antibiotic cleavage and kinetic transitions in Mycobacterium tuberculosis β-lactamase.