Genomic Background Governs Opposing Responses to Nalidixic Acid Upon Megaplasmid Acquisition in Pseudomonas
D. A. Baltrus, C. Smith, M. Derrick, C. Leligdon, Z. Rosenthal, M. Mollico, A. Moore, M. Clark
The paper shows that acquiring a megaplasmid can either sensitize or increase resistance to nalidixic acid in different Pseudomonas strains, depending on their genomic background.
bioRxiv · Jan 5, 2021Microbiology