Author

M. Domin

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Biophysics· 2 Bioengineering· 1 Microbiology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:deep learning· 2 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:protein folding & dynamics· 2 Approach:statistical model· 2 Organism:bacteria (other)· 1 Research Focus:benchmarking· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

B. Momeni· 4 shared M. Zaccaria· 4 shared D. R. Kish· 2 shared L. Dellafiora· 2 shared L. Genovese· 2 shared M. Reverberi· 2 shared N. Sandlin· 2 shared T. Nakajima· 2 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

4 shared papersBiophysics

B. Momeni

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Weakly alkaline conditions degrade aflatoxins through lactone ring opening

N. Sandlin, J. Lee, M. Zaccaria, M. Domin, B. Momeni

This study shows that weakly alkaline conditions can degrade aflatoxins by opening their lactone ring, reducing contamination without harsh chemicals.

bioRxiv · Oct 31, 2023 · PreprintBioengineering

Enzyme fatigue limits the detoxification of aflatoxin by Rhodococcus species

M. Zaccaria, N. Sandlin, D. H. Fu, M. Domin, B. Momeni

This study examines detoxification of aflatoxin by Rhodococcus species, finding that enzyme fatigue limits detoxification efficiency and that enzyme production is species- and environment-dependent.

bioRxiv · Aug 21, 2021 · PreprintMicrobiology

Mechanistic Insight from Full Quantum Mechanical Modeling: Laccase as a Detoxifier of Aflatoxins

M. Zaccaria, W. Dawson, D. R. Kish, M. Reverberi, M. C. Bonaccorsi di Patti, M. Domin, V. Cristiglio, L. Dellafiora, F. Gabel, T. Nakajima, L. Genovese, B. Momeni

The paper uses quantum mechanical modeling to show that low steric affinity, not oxidative activity, limits laccase's ability to detoxify aflatoxins, identifying key residues for enzyme optimization.

bioRxiv · Dec 31, 2020 · PreprintBiophysics

Full quantum mechanical modeling of the enzyme-substrate system: how laccase detoxifies aflatoxin

M. Zaccaria, W. Dawson, D. R. Kish, M. Reverberi, M. Domin, L. Dellafiora, T. Nakajima, L. Genovese, B. Momeni

This paper uses quantum mechanical modeling to study laccase detoxification of aflatoxin, identifying affinity limitations and environmental dependencies, and proposes a roadmap for enzyme optimization.

bioRxiv · Mar 2, 2020 · PreprintBiophysics