F. Gabel

Conformation and structural dynamics of the Xist lncRNA A-repeats

This study characterizes the conformational dynamics of Xist lncRNA A-repeats using an integrated approach of biochemical and biophysical techniques.

Binding stoichiometry and structural model of the HIV-1 Rev/Importin beta complex

This study determines the binding stoichiometry and structural model of the HIV-1 Rev/Importin beta complex using biochemical and biophysical methods.

Mechanistic Insight from Full Quantum Mechanical Modeling: Laccase as a Detoxifier of Aflatoxins

The paper uses quantum mechanical modeling to show that low steric affinity, not oxidative activity, limits laccase's ability to detoxify aflatoxins, identifying key residues for enzyme optimization.

Mechanistic insights into RNA binding and RNA-regulated RIG-I ubiquitination by TRIM25

This study identifies RNA binding sites on TRIM25 and shows that RNA binding enhances its E3 ligase activity and affects RIG-I ubiquitination.

Merging in-solution X-ray and neutron scattering data allows fine structural analysis of membrane-protein detergent complexes

The paper combines SAXS and SANS data to analyze unlabeled membrane-protein detergent complexes, providing more detailed structural information than either method alone.