Cancer BiologybioRxivPreprint
High Density Domain-Focused CRISPR Screens Reveal Novel Epigenetic Regulators of HOX/MEIS Activation in Acute Myeloid Leukemia
K. Barbosa, A. Deshpande, M. E. Perales…·A. J. Deshpande
The paper identifies SGF29 as a novel chromatin regulator of MEIS1 and AML oncogenes, showing its role in leukemogenesis and potential as a drug target.
DOI 10.1101/2022.12.12.519332