Loss of zinc transporters ZIP1 and ZIP3 augments platelet reactivity in response to G protein-coupled receptor agonists and accelerates thrombus formation in vivo
A. Elgheznawy, P. Oeftering, M. Englert, F. Kaiser, C. Kusch, U. Gbureck, M. R. Boesl, B. Nieswandt, T. Voegtle, H. M. Hermanns
This study shows that loss of ZIP1 and ZIP3 in mice leads to increased platelet reactivity and faster thrombus formation, despite normal Zn2+ levels.
bioRxiv · Nov 19, 2021 · PreprintBiochemistry