Author

A. Gerber

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3 Microbiology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Organism:mouse· 4 Assay:proteomics· 3 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell type annotation· 2 Research Focus:host-pathogen & immune response· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

D. Kaymak· 2 shared M.-F. Ritz· 2 shared P. Schmassmann· 2 shared S. Hogan· 2 shared T. A. Martins· 2 shared T. Shekarian· 2 shared A. A. Baig· 1 shared A. Beshirova· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

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Curved chords = mutual co-authorship

2 shared papersCancer Biology

D. Kaymak

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Enhancing anti-EGFRvIII CAR T cell therapy against glioblastoma with a paracrine SIRPγ-derived CD47 blocker

T. A. Martins, N. Tatari, D. Kaymak, S. Hogan, E. M. Bartoszek, R. Wieboldt, M.-F. Ritz, A. Buck, M. McDaid, A. Gerber, A. Beshirova, M. M. Etter, A. Heider, T. Shekarian, H. Mohamed, , G. Hutter

This paper develops a CAR T cell therapy that secretes a CD47 blocker to enhance anti-EGFRvIII efficacy against glioblastoma by modulating the tumor microenvironment.

bioRxiv · Aug 31, 2023Cancer Biology

Multidimensional analysis of matched primary and recurrent glioblastoma identifies Fcgamma receptors upregulation on microglia as a contributor of tumor recurrence.

T. Shekarian, S. Hogan, T. A. Martins, P. Schmassmann, A. Gerber, J. Roux, D. Kaymak, C. Durano, B. Burger, M. Matter, M.-F. Ritz, G. A. Hutter

This study identifies Fcgamma receptor upregulation on activated microglia in recurrent glioblastoma as a factor associated with shorter time-to-relapse.

bioRxiv · Apr 21, 2023 · PreprintCancer Biology

Microthrombocytopenia caused by impaired microtubule stability in RhoB-deficient mice

M. Englert, K. Aurbach, A. Gerber, T. Heib, I. C. Becker, L. M. Wackerbarth, C. Kusch, A. A. Baig, S. Duetting, U. G. Knaus, C. Stigloher, B. Nieswandt, I. Pleines, Z. Nagy

This study shows that RhoB deficiency in mice causes microthrombocytopenia due to impaired microtubule stability, distinct from RhoA's role.

bioRxiv · Nov 4, 2021 · PreprintCell Biology

Mapping the evolutionary landscape of Zika virus infection in immunocompromised mice.

M. G. Noval, M. V. Rangel, K. E. Johnson, E. De Jesus, A. Gerber, S. Schuster, K. Cadwell, E. Ghedin, K. A. Stapleford

This study establishes a ZIKV transmission model in immunocompromised mice to investigate factors influencing viral evolution and DVG production.

Virus Evolution · Dec 11, 2020Peer-reviewedMicrobiology

A histone-like motif in yellow fever virus contributes to viral replication

D. Mourao, S. Chen, U. Schaefer, L. Bozzacco, L. A. Carneiro, A. Gerber, C. Adura, B. D. Dill, H. Molina, T. Carroll, M. Paul, N. V. Bhanu, B. A. Garcia, G. Joberty, I. Rioja, , A. Tarakhovsky

This study identifies a histone-like motif in the yellow fever virus capsid protein that mimics histone H4 and interferes with BRD4-mediated gene regulation, impacting viral replication.

bioRxiv · May 5, 2020 · PreprintMicrobiology

Beyond Conventional Models: Recreating the Initiation, Evolution, and Genome of GBM

A. Bohm, J. DePetro, C. Binding, A. Gerber, N. Chahley, M. Ware, K. Thomas, S. Bukhari, C. Chen, E. Chahley, C. Grisdale, N. D. Berger, S. Lawn, Y. Yu, R. Wong, , G. Cairncross

This study develops a mouse model of glioblastoma (GBM) that replicates its genomic landscape and early stages, enabling research into prevention and treatment strategies.

bioRxiv · Nov 9, 2019 · PreprintCancer Biology