BiochemistrybioRxiv
Non-glycosylated IGF2 prohormones are more mitogenic than native IGF2
P. Potalitsyn, L. Mrazkova, I. Selicharova…·L. Zakova
The paper compares the mitogenic activity of different IGF2 proforms and finds that non-glycosylated pro-IGF2(156) and big-IGF2(104) have higher proliferative properties than native IGF2.
DOI 10.1038/s42003-023-05239-6