Principles of self-organization and load adaptation by the actin cytoskeleton during clathrin-mediated endocytosis
M. Akamatsu, R. Vasan, D. Serwas, M. Ferrin, P. Rangamani, D. G. Drubin
The paper uses a multiscale model to show that actin networks enable clathrin-mediated endocytosis by self-organizing and adapting to membrane tension through Arp2/3 complexes and bent filaments.
bioRxiv · Jun 21, 2019Cell Biology