M. Akamatsu

This study identifies biophysical mechanisms regulating non-muscle myosin 2 filament assembly using dynamic imaging and optogenetic tools, showing myosin monomer concentration and myosin:myosin interactions drive filament formation.

The paper uses cryo-electron tomography to study actin filament organization during clathrin-mediated endocytosis, revealing how actin dynamics generate pulling forces for vesicle formation.

The paper investigates how actin networks adapt to membrane tension during clathrin-mediated endocytosis, finding that actin assembly increases under elevated load to maintain CME robustness.

This study uses a mechanical model to show that non-axisymmetric buckling reduces the energy barrier for membrane neck constriction compared to symmetric necks.

The paper uses a multiscale model to show that actin networks enable clathrin-mediated endocytosis by self-organizing and adapting to membrane tension through Arp2/3 complexes and bent filaments.

This study uses differential scanning fluorimetry to analyze amino-acid binding to the T1r2a/T1r3LBD model receptor, showing thermal stabilization and specificity for L-amino acids.

The paper uses microscopy techniques to study interphase nodes in fission yeast, finding they have defined sizes and protein compositions, with type 1 nodes disassembling during mitosis and type 2 nodes remaining intact.

This study uses nanostructured substrates to control membrane curvature in live cells and finds that CME proteins prefer positive curvature, while other proteins do not.