Author
M. Ficarelli
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
Biology Disciplines
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2019-2022 · peak 2/yrCo-Author Collaboration Network
10 top collaborators · 44 mutual co-author links4 papers
Recent·Most cited
Regulation of KHNYN antiviral activity by the extended di-KH domain and nucleo-cytoplasmic trafficking
M. J. Lista, R. P. Galao, M. Ficarelli, D. Kmiec, H. Wilson, H. Winstone, E. R. Morris, H. E. Mischo, J. Wanford, R. Youle, C. Odendall, I. A. Taylor, S. J. Neil, C. Swanson
This paper identifies the extended di-KH and CUBAN domains in KHNYN as critical for its antiviral activity and interaction with ZAP, showing that the CUBAN domain regulates trafficking and abundance.
bioRxiv · Dec 22, 2021 · PreprintMicrobiology
The C-terminal PARP domain of the long ZAP isoform contributes essential effector functions for CpG-directed antiviral activity
D. Kmiec, M. J. Lista, M. Ficarelli, C. Swanson, S. J. D. Neil
This study identifies the C-terminal PARP domain and CaaX box of ZAP-L as essential for CpG-directed antiviral activity by modulating cofactor interactions and subcellular localization.
bioRxiv · Jun 22, 2021 · PreprintMicrobiology
KHNYN is essential for ZAP-mediated restriction of HIV-1 containing clustered CpG dinucleotides
M. Ficarelli, H. Wilson, R. Pedro Galao, S. Neil, C. M. Swanson
The paper identifies KHNYN as a novel ZAP cofactor essential for restricting HIV-1 with clustered CpG dinucleotides.
bioRxiv · Mar 18, 2019 · PreprintImmunology