Altered X-chromosome inactivation predisposes to autoimmunity
C. Huret, L. Ferraye, A. David, M. Mohamed, N. Valentin, F. Charlotte, M. Savignac, M. Goodhardt, J.-C. Guery, C. Rougeulle, C. Morey
This study shows that altered X-chromosome inactivation in female mice leads to autoimmune features similar to lupus.
bioRxiv · Apr 20, 2023Immunology