ENDO-LYSOSOME-TARGETED NANOPARTICLE DELIVERY OF ANTIVIRAL THERAPY FOR CORONAVIRUS INFECTIONS
A. Petcherski, B. Tingley, A. Martin, S. Adams, A. Brownstein, R. Steinberg, B. Shabane, C. Osto, J. Ngo, G. Garcia, M. Veliova, V. Arumugaswami, A. Colby, O. Shirihai, M. Grinstaff
This study develops lysosome-targeted nanoparticles loaded with mefloquine to inhibit coronavirus infection, showing effectiveness against SARS-CoV-2 and its variants in cell models.
bioRxiv · May 8, 2023 · PreprintBioengineering