Author

M. H. Schaefer

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3 Evolutionary Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Organism:human· 5 Approach:statistical model· 4 Assay:bulk RNA-seq· 3 Research Focus:gene regulatory network inference· 3 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Research Focus:chromatin & epigenetic regulation· 2

Frequent Co-Authors

L. Serrano· 3 shared X. Hernandez-Alias· 3 shared G. Senger· 2 shared H. Benisty· 2 shared M. Irimia· 2 shared M. Weber· 2 shared A. D. Macandog· 1 shared A. Torres-Mendez· 1 shared

Activity by Year

2019-2022 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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Curved chords = mutual co-authorship

3 shared papersCancer Biology

L. Serrano

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Evolutionary conservation of A/T-ending codons reflects co-regulation of expression and complex formation.

H. Benisty, X. Hernandez-Alias, M. Weber, M. Anglada-Girotto, F. Mantica, L. Radusky, G. Senger, D. Weghorn, M. Irimia, M. H. Schaefer, L. Serrano

The paper shows that A/T-ending codons are conserved and co-regulated, enabling coordinated protein expression and complex formation across vertebrates.

bioRxiv · Jan 17, 2022Evolutionary Biology

GZMKhigh CD8+ T effector memory cells are associated with CD15high neutrophil abundance in early-stage colorectal tumors and predict poor clinical outcome.

S. Tiberti, C. Catozzi, C. Scirgolea, O. Croci, M. Ballerini, D. Cagnina, C. Soriani, A. D. Macandog, C. B. Nava Lauson, G. Bertalot, W. L. Petz, S. P. Ravenda, V. Licursi, P. Paci, M. Rasponi, , T. o. MANZO

The paper identifies GZMKhigh CD8+ T effector memory cells in early-stage CRC tumors, which correlate with neutrophil abundance and predict poor clinical outcomes.

bioRxiv · Dec 14, 2021Immunology

Regulation of protein complex partners as a compensatory mechanism in aneuploid tumors

G. Senger, S. Santaguida, M. H. Schaefer

The paper investigates how aneuploid tumors regulate protein complex partners to compensate for chromosome imbalance, finding post-transcriptional control impacts survival.

bioRxiv · Dec 5, 2021Cancer Biology

Hypersilencing of SRRM4 suppresses basal microexon inclusion and promotes tumor growth across cancers

S. A. Head, X. Hernandez-Alias, J.-S. Yang, V. Beltran-Sastre, A. Torres-Mendez, M. Irimia, M. H. Schaefer, L. Serrano

This study shows that SRRM4 silencing in tumors suppresses microexon inclusion and promotes tumor growth by shifting cells toward differentiation.

PLOS Biology · Feb 23, 2021Peer-reviewedCancer Biology

Proliferation specific codon usage facilitates oncogene translation

H. Benisty, M. Weber, X. Hernandez-Alias, M. H. Schaefer, L. Serrano

The paper shows that oncogenes with codon usage adapted for efficient translation in proliferative cells are more frequently mutated in cancer.

bioRxiv · Jul 11, 2019Cancer Biology