L. Serrano

Finding Fluorescence: Utilizing community science to document novel biofluorescence occurrences and encourage community engagement in science

This paper introduces Finding Fluorescence, a community science platform that documents novel biofluorescence occurrences and highlights the ecological roles of fluorescence across species.

The BRD4S-LOXL2-MED1 interaction at the forefront of cell cycle transcriptional control in triple-negative breast cancer

This study shows that inhibiting LOXL2 and BRD4 together reduces triple-negative breast cancer proliferation by disrupting the BRD4S-LOXL2-MED1 interaction that controls cell cycle gene expression.

Early Endosome Capture Proteomics and its Application to Amyloid Precursor Protein Intramembrane Processing by β and γ-Secretases

This paper develops a method to isolate early endosomes and uses it to study amyloid precursor protein processing by β and γ-secretases in these compartments.

Evolutionary conservation of A/T-ending codons reflects co-regulation of expression and complex formation.

The paper shows that A/T-ending codons are conserved and co-regulated, enabling coordinated protein expression and complex formation across vertebrates.

Hypersilencing of SRRM4 suppresses basal microexon inclusion and promotes tumor growth across cancers

This study shows that SRRM4 silencing in tumors suppresses microexon inclusion and promotes tumor growth by shifting cells toward differentiation.

LoxTnSeq: Random Transposon insertions combined with cre/lox recombination and counterselection to generate large random genome reductions

LoxTnSeq generates genome reduction mutants by combining transposon mutagenesis, Cre/Lox recombination, and deep-sequencing, identifying 285 unique deletions in Mycoplasma pneumoniae.

Proliferation specific codon usage facilitates oncogene translation

The paper shows that oncogenes with codon usage adapted for efficient translation in proliferative cells are more frequently mutated in cancer.