J.-S. Yang

Ether lipids influence cancer cell fate by modulating iron uptake

This study shows that ether lipids in cancer cells regulate membrane properties to influence iron uptake, ferroptosis, and metastasis, offering a therapeutic target.

DYRKP kinase regulates cell wall degradation in Chlamydomonas by inducing matrix metalloproteinase expression

This study identifies DYRKP kinase as a regulator of cell wall degradation in Chlamydomonas by inducing MMP expression, enabling daughter cell hatching.

Evaluation of antiviral drugs against newly emerged SARS-CoV-2 Omicron variants

This study evaluates the antiviral efficacy of remdesivir, molnupiravir, and nirmatrelvir against newly emerged SARS-CoV-2 Omicron subvariants and finds they retain antiviral activity.

Relative infectivity of the SARS-CoV-2 Omicron variant in human alveolar cells

This study compares the infectivity of SARS-CoV-2 variants in human alveolar cells, finding Omicron (BA.1) to be 3-5-fold more infectious than other variants at early infection.

The in vitro and in vivo potency of CT-P59 against Delta and its associated variants of SARS-CoV-2

This study evaluates CT-P59's antiviral activity against Delta and its variants, showing reduced in vitro potency but effective in vivo neutralization and symptom remission in mice.

Hypersilencing of SRRM4 suppresses basal microexon inclusion and promotes tumor growth across cancers

This study shows that SRRM4 silencing in tumors suppresses microexon inclusion and promotes tumor growth by shifting cells toward differentiation.

Zoom in on Ca2+ pattern and ion flux dynamics to decode spatial and temporal regulation of cotton fiber growth

The paper uses confocal imaging and ion flux measurements to show that cotton fiber growth is diffusive, not tip growth, and responds to H2O2 with increased ion efflux.

rec-Y2H matrix screening reveals a vast potential for direct protein-protein interactions among RNA binding proteins

The paper uses rec-Y2H screening to identify direct protein-protein interactions among RNA-binding proteins, revealing new interactions and their implications for RNA processing and cancer.

Regulated compartmentalization of enzymes in Golgi by GRASP55 controls cellular glycosphingolipid profile and function

This study identifies GRASP55 as a regulator of enzyme compartmentalization in the Golgi, which controls glycosphingolipid biosynthesis and cellular glycan profiles.