Cancer BiologybioRxiv
Steroid Receptor Coactivator-3 is a Key Modulator of Regulatory T Cell-Mediated Tumor Evasion
S. J. Han, P. Jain, Y. Gilad…·B. W. O'Malley
This study shows that deleting SRC-3 in regulatory T cells eradicates tumors in mouse models by enhancing antitumor immunity without autoimmune side effects.
DOI 10.1073/pnas.2221707120