ERBB-activated myofibroblastic cancer-associated fibroblasts promote local metastasis of pancreatic cancer
G. Mucciolo, J. Araos Henriquez, S. Pinto Teles, J. S. Manansala, M. Jihad, W. Li, E. G. Lloyd, P. S. W. Cheng, G. Biffi
This study identifies ERBB signaling in myofibroblastic CAFs as a driver of local PDAC metastasis and suggests its potential as a therapeutic target.
Cancer Cell · Jan 1, 2024Peer-reviewedCancer Biology