Author

M. Klunk

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2

Frequent Co-Authors

A. A. Ordonez· 2 shared S. K. Jain· 2 shared S. Krug· 2 shared W. Bishai· 2 shared B. G. Kang· 1 shared C. A. Ruiz-Bedoya· 1 shared G. Srikrishna· 1 shared I. Kramnik· 1 shared

Activity by Year

2021-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

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2 shared papersMicrobiology

A. A. Ordonez

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2 papers

Recent·Most cited

Adjunctive inhibition of the integrated stress response pathway accelerates bacterial clearance in a mouse model of tuberculosis

S. Krug, P. Prasad, S. Xiao, S. Lun, C. A. Ruiz-Bedoya, M. Klunk, A. A. Ordonez, S. K. Jain, G. Srikrishna, I. Kramnik, W. Bishai

This study shows that inhibiting the Integrated Stress Response (ISR) pathway alongside standard TB antibiotics reduces bacterial loads and accelerates sterilization in a mouse model of tuberculosis.

bioRxiv · Dec 31, 2021 · PreprintMicrobiology

Host regulator PARP1 contributes to sex differences and immune responses in a mouse model of tuberculosis

S. Krug, A. A. Ordonez, M. Klunk, B. G. Kang, S. K. Jain, T. M. Dawson, V. L. Dawson, W. Bishai

This study identifies PARP1 as a key regulator of sex differences and immune responses in a mouse model of tuberculosis, showing it enhances early proinflammatory responses in males but impairs containment in females.

bioRxiv · Apr 21, 2021 · PreprintImmunology