Deciphering Oxygen Distribution and Hypoxia Profiles in the Tumor Microenvironment: A Data-Driven Mechanistic Modeling Approach
P. Kumar, M. Lacroix, P. Dupre, J. Arslan, L. Fenou, B. Orsetti, L. Le Cam, D. Racoceanu, O. Radulescu
The paper develops a data-driven mechanistic model to quantify hypoxia profiles in tumors using reaction-diffusion equations and vascular data.
bioRxiv · Mar 4, 2024Cancer Biology