AMPK-Fyn signaling promotes Notch1 stability to potentiate hypoxia-induced breast cancer stemness and drug resistance
M. Lahiry, S. Kumar, K. Hari, A. Chedere, M. K. Jolly, A. Rangarajan
This study shows AMPK-Fyn signaling stabilizes cleaved Notch1 under hypoxia, enhancing breast cancer stemness and drug resistance.
bioRxiv · Apr 21, 2020 · PreprintCancer Biology