Author

A. Chedere

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 3 Approach:statistical model· 3 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Assay:metagenomics· 1 Assay:proteomics· 1

Frequent Co-Authors

A. Rangarajan· 3 shared M. K. Jolly· 3 shared K. Hari· 2 shared S. Kumar· 2 shared H. Levine· 1 shared M. Lahiry· 1 shared P. Chakraborty· 1 shared S. Tripathi· 1 shared

Activity by Year

2020-2020 · peak 3/yr

Co-Author Collaboration Network

9 top collaborators · 24 mutual co-author links

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3 shared papersCancer Biology

A. Rangarajan

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Author profile →

3 papers

Recent·Most cited

Multistability and consequent phenotypic plasticity in AMPK-Akt double negative feedback loop in cancer cells

A. Chedere, K. Hari, S. Kumar, A. Rangarajan, M. K. Jolly

The paper develops a mathematical model of the AMPK-Akt feedback loop, showing it can generate multistability and phenotypic switching in cancer cells, supported by experimental and clinical data.

bioRxiv · Dec 21, 2020Cancer Biology

Epigenetic feedback and stochastic partitioning during cell division can drive resistance to EMT

W. Jia, S. Tripathi, P. Chakraborty, A. Chedere, A. Rangarajan, H. Levine, M. K. Jolly

This study identifies two mechanisms—epigenetic feedback in the ZEB1/GRHL2 loop and stochastic partitioning during cell division—that can drive resistance to EMT in cancer cells.

Oncotarget · Jul 7, 2020Peer-reviewedCancer Biology

AMPK-Fyn signaling promotes Notch1 stability to potentiate hypoxia-induced breast cancer stemness and drug resistance

M. Lahiry, S. Kumar, K. Hari, A. Chedere, M. K. Jolly, A. Rangarajan

This study shows AMPK-Fyn signaling stabilizes cleaved Notch1 under hypoxia, enhancing breast cancer stemness and drug resistance.

bioRxiv · Apr 21, 2020 · PreprintCancer Biology