Histone H3K27me3 demethylases regulate human Th17 cell development and effector functions by impacting on metabolism
A. P. Cribbs, S. Terlecki-Zaniewicz, M. Philpott, J. Baardman, D. Ahern, M. Lindow, S. Obad, H. Oerum, B. Sampey, P. Mander, H. Penn, P. Wordsworth, P. Bowness, R. K. Prinjha, M. de Winther, , U. Oppermann
This study identifies KDM6A and KDM6B as regulators of human Th17 cell development and effector functions by affecting metabolism and cytokine production.
bioRxiv · Oct 30, 2019Immunology