Author

P. Bowness

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 4

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 4 Organism:human· 4 Research Focus:differential expression· 3 Approach:experimental assay· 3 Assay:scRNA-seq· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

F. Penkava· 3 shared A. Lledo Lara· 2 shared A. Maroof· 2 shared D. Simone· 2 shared N. Yager· 2 shared S. Cole· 2 shared A. L. Croxford· 1 shared A. P. Cribbs· 1 shared

Activity by Year

2019-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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3 shared papersImmunology

F. Penkava

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Author profile →

4 papers

Recent·Most cited

Single cell analysis of spondyloarthritis regulatory T cells identifies distinct synovial gene expression patterns and clonal fates

D. Simone, F. Penkava, A. Ridley, S. N. Sansom, H. M. Al-Mossawi, P. Bowness

The paper analyzes single-cell transcriptomes of Tregs from spondyloarthritis patients to identify distinct gene expression patterns and clonal fates in synovial tissue.

bioRxiv · May 31, 2021Immunology

Ex vivo mass cytometry analysis reveals a profound myeloid proinflammatory signature in psoriatic arthritis synovial fluid

N. Yager, S. Cole, A. Lledo Lara, A. Maroof, F. Penkava, J. Knight, P. Bowness, H. Al-Mossawi

The paper uses mass cytometry and transcriptomic analysis to identify proinflammatory myeloid cell signatures in psoriatic arthritis synovial fluid.

bioRxiv · Mar 4, 2021Immunology

Histone H3K27me3 demethylases regulate human Th17 cell development and effector functions by impacting on metabolism

A. P. Cribbs, S. Terlecki-Zaniewicz, M. Philpott, J. Baardman, D. Ahern, M. Lindow, S. Obad, H. Oerum, B. Sampey, P. Mander, H. Penn, P. Wordsworth, P. Bowness, R. K. Prinjha, M. de Winther, , U. Oppermann

This study identifies KDM6A and KDM6B as regulators of human Th17 cell development and effector functions by affecting metabolism and cytokine production.

bioRxiv · Oct 30, 2019Immunology

Single-cell sequencing reveals a clonal expansion of pro-inflammatory synovial CD8 T cells expressing tissue homing receptors in psoriatic arthritis

F. Penkava, M. Del Castillo Velasco-Herrera, M. D. Young, N. Yager, A. Lledo Lara, C. Guzzo, A. Maroof, L. Mamanova, S. Cole, M. Efremova, D. Simone, C. C. Brown, A. L. Croxford, S. Teichmann, P. Bowness, , M. H. Al-Mossawi

The paper identifies clonal expansion of pro-inflammatory CD8 T cells in psoriatic arthritis joints using single-cell sequencing and links them to tissue homing receptors and antigen specificity.

bioRxiv · Jul 16, 2019Immunology