Author

D. Ahern

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Organism:human· 3 Research Focus:differential expression· 2 Assay:flow cytometry· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Research Focus:clustering· 1

Frequent Co-Authors

A. Rendek· 2 shared U. Oppermann· 2 shared Z. Soonawalla· 2 shared A. Easton· 1 shared A. P. Cribbs· 1 shared B. Sampey· 1 shared E. Abu-Shah· 1 shared E. H. Arbe-Barnes· 1 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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2 shared papersCancer Biology

A. Rendek

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Author profile →

3 papers

Recent·Most cited

High-dimensional mass cytometry reveals stemness state heterogeneity in pancreatic ductal adenocarcinoma

E. H. Ervin, D. Ahern, F. Liu, A. Rendek, Z. Soonawalla, U. Oppermann, P. Hulley, S. Pauklin

The paper uses mass cytometry to analyze stemness states in PDAC, revealing molecular heterogeneity and identifying a subset with plastic phenotypes.

bioRxiv · Feb 27, 2024 · PreprintCancer Biology

Immune responses in pancreatic cancer may be restricted byprevalence of activated regulatory T-cells, dysfunctionalCD8+ T-cells, and senescent T-cells

S. Sivakumar, E. Abu-Shah, D. Ahern, E. H. Arbe-Barnes, N. Mangal, S. Reddy, A. Rendek, A. Easton, E. Kurz, M. Silva, L. R. Heij, Z. Soonawalla, R. Bashford-Rogers, M. R. Middleton, M. Dustin

This study identifies immune cell states in pancreatic cancer, showing regulatory T-cells and dysfunctional CD8+ T-cells contribute to a suppressive microenvironment, suggesting new therapeutic targets.

bioRxiv · Jun 20, 2020 · PreprintImmunology

Histone H3K27me3 demethylases regulate human Th17 cell development and effector functions by impacting on metabolism

A. P. Cribbs, S. Terlecki-Zaniewicz, M. Philpott, J. Baardman, D. Ahern, M. Lindow, S. Obad, H. Oerum, B. Sampey, P. Mander, H. Penn, P. Wordsworth, P. Bowness, R. K. Prinjha, M. de Winther, , U. Oppermann

This study identifies KDM6A and KDM6B as regulators of human Th17 cell development and effector functions by affecting metabolism and cytokine production.

bioRxiv · Oct 30, 2019Immunology