Natural malaria infection elicits rare but potent neutralizing antibodies to the blood-stage antigen RH5
L. T. Wang, A. J. R. Cooper, B. Farrell, K. Miura, A. Diouf, N. Muller-Sienerth, C. Crosnier, L. Purser, M. Maciuszek, J. R. Barrett, K. McHugh, C. Tucker, S. Li, S. Doumbo, D. Doumtabe, , J. Tan
The paper identifies potent neutralizing antibodies against the malaria antigen RH5 from natural infection, showing they target similar epitopes as vaccine-induced antibodies.
bioRxiv · Oct 4, 2023Immunology