An acute immune response underlies the benefit of cardiac adult stem cell therapy
R. Vagnozzi, M. Maillet, M. Sargent, H. Khalil, A. K. Johansen, J. Schwanekamp, A. J. York, V. Huang, M. Nahrendorf, S. Sadayappan, J. D. Molkentin
This study shows that cardiac adult stem cell therapy improves heart function through an acute immune response involving macrophages, not by regenerating cardiomyocytes.
bioRxiv · Dec 26, 2018Cell Biology