Quantitative single cell heterogeneity profiling of patient derived tumor initiating gliomaspheres reveals unique signatures of malignancy and response
M. Masterman-Smith, N. A. Graham, E. Panosyan, J. Mottahedeh, E. E. Samuels, A. Nunez, S. H. Lim, T. Phillips, M. Choe, K. Visnyei, W. H. Yong, T. G. Graeber, M.-F. Lang, H. Kornblum, J. Sun
The paper uses single cell proteomic analysis to identify distinct signaling phenotypes in gliomaspheres, revealing EGFR and AKT/TORC1 signaling divergence and potential therapeutic targets.
bioRxiv · Jan 14, 2020 · PreprintCancer Biology