Functional Changes to Achilles Tendon and Enthesis in a Mouse Model of an Adolescent Masculine Gender-Affirming Hormone Treatment
L. A. Hold, T. Phillips, P. Cordts, S. Steltzer, S.-H. Bae, B. W. Henry, N. Migotsky, S. Grossman, C. D. Cruz, V. Padmanabhan, M. Moravek, A. Shikanov, A. C. Abraham, M. L. Killian
This study examines how puberty suppression and testosterone affect Achilles tendon and enthesis properties in a mouse model of transmasculine gender-affirming hormone therapy, finding improved load capacity and increased cell density with GnRHa treatment.
bioRxiv · Jun 10, 2024 · PreprintPhysiology