Activin A correlates with the worst outcomes in COVID-19 patients, and can be induced by cytokines via the IKK/NF-kappa B pathway
M. McAleavy, Q. Zhang, J. Xu, L. Pan, M. Wakai, P. J. Ehmann, M. F. Wipperman, T. Shavlakadze, S. C. Hamon, A. Boyapati, L. G. Morton, C. A. Kyratsous, D. J. Glass
The paper shows elevated Activin A and FLRG levels in COVID-19 patients predict severe outcomes like mechanical ventilation and mortality.
bioRxiv · Feb 4, 2021 · PreprintImmunology